Botanical name: Silybum marianum
Common name:
Milk Thistle, Marian Thistle, St Mary’s Thistle
Part (s) used: Seed (dried fruit)
Common Usage of Milk Thistle
- Supports normal liver function
- Helps reverse liver damage caused by alcohol,
drug, dietary abuse, and exposure to chemicals
that threaten normal liver function - Increases breast milk production in nursing mothers
- Helps repair skin conditions, (jaundice,
varicose veins), related to poor liver function - Alleviates allergies associated with liver damage
Milk thistle is native to the Mediterranean and also grows wild throughout North America, Australia, and Europe, where it has been used for thousands of years as a remedy for liver problems. Milk thistle is toxic to livestock, and it forms dense stands in pastures and
rangelands.
The leaves are very distinctive, with white marbling on the shiny green leaves.
The dried fruit of milk thistle contains a flavonoid complex known as silymarin which is made up of silibinin, silidianin, and silicristin.
Silibinin is the most active component and is considered to be the constituent responsible for the benefits
attributed to silymarin. Both the active bioflavonoid complex, silymarin
and it's sub-component silibinin, are powerful antioxidants which exert a protective
effect against substances that may be potentially harmful to the liver.
Milk thistle extract is most commonly recommended to counteract the harmful
actions of alcohol on the liver. Double-blind clinical studies show that it helps the
liver return to a healthy state once a person stops drinking. Some trials suggest it may improve quality of life and even life expectancy in people with liver cirrhosis. However, another trial found no effect in cirrhosis patients.
Dosage
For liver disease and/or diminished liver function, research results indicate the use of 420–600 mg of silymarin per day from an herbal extract of milk thistle standardized to 80% silymarin content. Results should become noticable in about eight to twelve weeks. Milk thistle extract may be considered for long-term therapy for people with chronic liver disease.
Research
The
Clinical Utility of Milk Thistle (Silybum marianum) in Cirrhosis of the Liver,
Boerth J, Strong KM. J. Herb Pharmcother, 2002.
Phenolics-rich
extracts from Silybum marianum and Prunella vulgaris reduce a high-sucrose diet
induced oxidative stress in hereditary hypertriglyceridemic rats.
Skottova
N, Kazdova L, Oliyarnyk O, Vecera R, Sobolova L, Ulrichova J. Institute of
Pharmacology,
Medical Faculty, Czech Republic, Aug 2004.
Silymarin
retards the progression of alcohol-induced hepatic fibrosis in baboons.
Lieber CS, Leo MA, Cao Q, Ren C, DeCarli LM. Oct 2003
Silibinin
protects mice from T cell-dependent liver injury.
Schumann J, Prockl J,
Kiemer AK, Vollmar AM, Bang R, Tiegs G. Institute of Experimental and Clinical
Pharmacology and Toxicology, University of Erlangen-Nuremberg, Germany, Sept
2003.
Milk
thistle: is there a role for its use as an adjunct therapy in patients with
cancer?
Ladas EJ, Kelly KM. Division of Pediatric Oncology, Columbia
University, New York, NY, USA. Jun 2003.
Articles
"Milk Thistle: Help for Your Liver", Chris Kilham, www.medicinehunter.com.
